| In late pregnancy CELEBREX should be avoided because it may cause problems in the final development of the heart in the fetus. - If you have liver disease. The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. DO NOT TAKE VIOXX IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to aspirin or any medicine containing aspirin or to a nonsteroidal anti-inflammatory drug (such as Feldene, Motrin, Naprosyn, Clinoril). A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to Vioxx or if a certain medicine is a nonsteroidal anti-inflammatory drug, contact your doctor or pharmacist. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of Vioxx unless your doctor tells you to do so. DO NOT EXCEED THE RECOMMENDED DOSE or take Vioxx for longer than prescribed without checking with your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using Vioxx. ALCOHOL WARNING: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take Vioxx or other pain relievers/fever reducers. This medicine may cause stomach bleeding. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. This includes any medicines that contain ibuprofen, naproxen, or ketoprofen. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using Vioxx during pregnancy. IT IS UNKNOWN IF VIOXX IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking Vioxx. - In Rheumatoid Arthritis, the recommended dose for CELEBREX is 100 mg to 200 mg, twice a day. CELEBREX provides relief through the day and through the night. Include on your medical history/personal profile all of the other medicines you are taking or plan to take while you are on VIOXX, even other medicines that you can get without a prescription. VIOXX has significant drug interactions with : If you are one of the many people who take low-dose aspirin for the prevention of heart attack or stroke, you can still take CELEBREX. However, taking CELEBREX and aspirin together can increase your risk for developing stomach ulcers compared to taking CELEBREX alone. CELEBREX is not a substitute for aspirin for heart attack or stroke prevention. In late pregnancy CELEBREX should be avoided because it may cause problems in the final development of the heart in the fetus. Serious but rare side effects that have been reported in patients taking CELEBREX are delineated below : - In analgesia and dysmenorrhea, the recommended dose for VIOXX is also 25 to 50 mg once a day. VIOXX provides relief through the day and through the night. SIDE EFFECTS that may occur while taking Vioxx include weakness or nausea. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience itching or skin rash, swelling of the feet or ankles, unexpected weight gain, vomiting material that looks like coffee grounds, or blood in stool or vomit. CONTACT YOUR DOCTOR IMMEDIATELY if you experience swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness; flu-like symptoms; sluggishness; yellowing of the skin or eyes; stomach pain; dark urine or pale stools; or unusual fatigue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. - have had an allergic reaction to celecoxib, which is the active ingredient of CELEBREX any of its inactive ingredients. This medication may be taken with food or immediately after meals to prevent stomach upset. Take this as directed. Do not increase your dose or take it more often than prescribed. This medication provides temporary relief and must be used in addition to rest, physical therapy and other measures. Because this medication makes an injury temporarily feel better, do not attempt to lift or exercise too soon. Follow your doctor's instructions for recovery. IS CELEBREX A SUBSTITUTE FOR CORTICOSTEROIDS? The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. - If you are breast-feeding or plan to breast-feed. It is not known whether Celebrex is passed through to human breast milk and what its effects could be on a nursing child. Tell your doctor your medical history, especially of: any liver or kidney disease, blood disorders, porphyria, asthma, any allergies. When rising quickly from a sitting or lying position, dizziness or lightheadedness may occur. Change positions slowly. Use caution engaging in activities requiring alertness (such as driving) if this drug makes you dizzy or drowsy. Limit alcohol intake while taking this medication. This drug should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Carisoprodol is excreted into breast milk. Consult your doctor before breast-feeding. Tell your doctor of all over-the-counter and prescription medication you may take including: sedatives, tranquilizers, sleeping pills, narcotic pain relievers, medication for depression and certain antihistamines (e.g., diphenhydramine). Many cough-and-cold products contain antihistamines, which can cause drowsiness. Check labels carefully and consult your pharmacist if you have any questions. Do not start or stop any medicine without doctor or pharmacist approval. - If you are breast-feeding or plan to breast-feed. It is not known whether Celebrex is passed through to human breast milk and what its effects could be on a nursing child. INCLUDE IN YOUR MEDICAL HISTORY/PERSONAL PROFILE : - In analgesia and dysmenorrhea, the recommended dose for VIOXX is also 25 to 50 mg once a day. VIOXX provides relief through the day and through the night. SIDE EFFECTS that may occur while taking Vioxx include weakness or nausea. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience itching or skin rash, swelling of the feet or ankles, unexpected weight gain, vomiting material that looks like coffee grounds, or blood in stool or vomit. CONTACT YOUR DOCTOR IMMEDIATELY if you experience swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness; flu-like symptoms; sluggishness; yellowing of the skin or eyes; stomach pain; dark urine or pale stools; or unusual fatigue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. Include on your medical history/personal profile all of the other medicines you are taking or plan to take while you are on CELEBREX, even other medicines that you can get without a prescription. Do not take CELEBREX if you: - If you are breast-feeding or plan to breast-feed. It is not known whether Celebrex is passed through to human breast milk and what its effects could be on a nursing child. - Methotrexate (a medicine used to suppress the immune system). - If you have liver disease. DO NOT TAKE VIOXX IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to aspirin or any medicine containing aspirin or to a nonsteroidal anti-inflammatory drug (such as Feldene, Motrin, Naprosyn, Clinoril). A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to Vioxx or if a certain medicine is a nonsteroidal anti-inflammatory drug, contact your doctor or pharmacist. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of Vioxx unless your doctor tells you to do so. DO NOT EXCEED THE RECOMMENDED DOSE or take Vioxx for longer than prescribed without checking with your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using Vioxx. ALCOHOL WARNING: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take Vioxx or other pain relievers/fever reducers. This medicine may cause stomach bleeding. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. This includes any medicines that contain ibuprofen, naproxen, or ketoprofen. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using Vioxx during pregnancy. IT IS UNKNOWN IF VIOXX IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking Vioxx. This medication may cause stomach upset, heartburn, headache, dizziness or drowsiness. If these symptoms persist or worsen, notify your doctor promptly. Inform your doctor promptly if you develop: persistent stomach pain, rapid heart rate. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. |