| - Methotrexate (a medicine used to suppress the immune system). CAN I TAKE CELEBREX IF I AM TAKING OTHER MEDICATIONS? DO NOT TAKE VIOXX IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to aspirin or any medicine containing aspirin or to a nonsteroidal anti-inflammatory drug (such as Feldene, Motrin, Naprosyn, Clinoril). A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to Vioxx or if a certain medicine is a nonsteroidal anti-inflammatory drug, contact your doctor or pharmacist. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of Vioxx unless your doctor tells you to do so. DO NOT EXCEED THE RECOMMENDED DOSE or take Vioxx for longer than prescribed without checking with your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using Vioxx. ALCOHOL WARNING: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take Vioxx or other pain relievers/fever reducers. This medicine may cause stomach bleeding. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. This includes any medicines that contain ibuprofen, naproxen, or ketoprofen. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using Vioxx during pregnancy. IT IS UNKNOWN IF VIOXX IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking Vioxx. - Lithium (a medicine used to treat a certain type of depression). - Methotrexate (a medicine used to suppress the immune system). - ACE inhibitors (medicines used for high blood pressure and heart failure). - Serious allergic reactions including swelling of the face, lips, tongue, and/or throat which may cause difficulty breathing or swallowing and wheezing occur rarely but may require treatment right away. Severe skin reactions have also been reported. The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Vioxx is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and to treat pain and menstrual discomfort. - If you are breast-feeding or plan to breast-feed. It is not known whether Celebrex is passed through to human breast milk and what its effects could be on a nursing child. NO. CELEBREX cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. Abrupt discontinuation of this medicine may lead to exacerbation of corticosteroid-responsive illness. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue this medication. - Rifampin (an antibiotic). - If you have had an allergic reaction to aspirin or other NSAIDs. - If you have had an allergic reaction to aspirin or other NSAIDs. |