| - Warfarin (a blood thinner). The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. - Lithium (a medicine used to treat a certain type of depression). - Severe liver problems, including hepatitis, jaundice and liver failure, occur rarely in patients taking NSAIDs, including CELEBREX. Symptoms of liver problems include nausea, tiredness, itching, tenderness in the right upper abdomen, and flu-like symptoms. - You should continue to take CELEBREX as prescribed even when you are feeling better. CELEBREX can be taken with or without food. NO. CELEBREX cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. Abrupt discontinuation of this medicine may lead to exacerbation of corticosteroid-responsive illness. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue this medication. - Lithium (a medicine used to treat a certain type of depression). The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any of our products. - Methotrexate (a medicine used to suppress the immune system). Vioxx is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and to treat pain and menstrual discomfort. - Methotrexate (a medicine used to suppress the immune system). - Warfarin (a blood thinner). You should continue to take VIOXX as prescribed even when you are feeling better. VIOXX can be taken with or without food. Generic VIOXX capsules come in 25mg. - You should continue to take CELEBREX as prescribed even when you are feeling better. CELEBREX can be taken with or without food. IS CELEBREX A SUBSTITUTE FOR CORTICOSTEROIDS? DO NOT TAKE VIOXX IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to aspirin or any medicine containing aspirin or to a nonsteroidal anti-inflammatory drug (such as Feldene, Motrin, Naprosyn, Clinoril). A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to Vioxx or if a certain medicine is a nonsteroidal anti-inflammatory drug, contact your doctor or pharmacist. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of Vioxx unless your doctor tells you to do so. DO NOT EXCEED THE RECOMMENDED DOSE or take Vioxx for longer than prescribed without checking with your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using Vioxx. ALCOHOL WARNING: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take Vioxx or other pain relievers/fever reducers. This medicine may cause stomach bleeding. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. This includes any medicines that contain ibuprofen, naproxen, or ketoprofen. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using Vioxx during pregnancy. IT IS UNKNOWN IF VIOXX IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking Vioxx. Serious but rare side effects that have been reported in patients taking CELEBREX are delineated below : - In Osteoarthritis, the recommended dose for VIOXX is 25 to 50 mg a day. VIOXX delivers 24-hour relief from a once-daily dose. CAN I TAKE CELEBREX IF I AM TAKING OTHER MEDICATIONS? - Serious stomach problems, such as stomach and intestinal bleeding, can occur with or without warning symptoms. These problems, if severe, could lead to hospitalization or death. Although this happens rarely, you should watch for signs that you may have this serious side effect. - If you have liver disease. CAN I TAKE CELEBREX IF I AM PREGNANT? In late pregnancy CELEBREX should be avoided because it may cause problems in the final development of the heart in the fetus. - You should continue to take CELEBREX as prescribed even when you are feeling better. CELEBREX can be taken with or without food. - Serious allergic reactions including swelling of the face, lips, tongue, and/or throat which may cause difficulty breathing or swallowing and wheezing occur rarely but may require treatment right away. Severe skin reactions have also been reported. |