| Include on your medical history/personal profile all of the other medicines you are taking or plan to take while you are on CELEBREX, even other medicines that you can get without a prescription. If you are one of the many people who take low-dose aspirin for the prevention of heart attack or stroke, you can still take CELEBREX. However, taking CELEBREX and aspirin together can increase your risk for developing stomach ulcers compared to taking CELEBREX alone. CELEBREX is not a substitute for aspirin for heart attack or stroke prevention. In late pregnancy CELEBREX should be avoided because it may cause problems in the final development of the heart in the fetus. - Warfarin (a blood thinner). In late pregnancy CELEBREX should be avoided because it may cause problems in the final development of the heart in the fetus. CELEBREX has significant drug interactions with : Vioxx is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and to treat pain and menstrual discomfort. - Methotrexate (a medicine used to suppress the immune system). - Severe liver problems, including hepatitis, jaundice and liver failure, occur rarely in patients taking NSAIDs, including CELEBREX. Symptoms of liver problems include nausea, tiredness, itching, tenderness in the right upper abdomen, and flu-like symptoms. The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. This medication may be taken with food or immediately after meals to prevent stomach upset. Take this as directed. Do not increase your dose or take it more often than prescribed. This medication provides temporary relief and must be used in addition to rest, physical therapy and other measures. Because this medication makes an injury temporarily feel better, do not attempt to lift or exercise too soon. Follow your doctor's instructions for recovery. - In analgesia and dysmenorrhea, the recommended dose for VIOXX is also 25 to 50 mg once a day. VIOXX provides relief through the day and through the night. SIDE EFFECTS that may occur while taking Vioxx include weakness or nausea. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience itching or skin rash, swelling of the feet or ankles, unexpected weight gain, vomiting material that looks like coffee grounds, or blood in stool or vomit. CONTACT YOUR DOCTOR IMMEDIATELY if you experience swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness; flu-like symptoms; sluggishness; yellowing of the skin or eyes; stomach pain; dark urine or pale stools; or unusual fatigue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. - ACE inhibitors (medicines used for high blood pressure and heart failure). - If you have high blood pressure. - ACE inhibitors (medicines used for high blood pressure and heart failure). - ACE inhibitors (medicines used for high blood pressure and heart failure). - Serious allergic reactions including swelling of the face, lips, tongue, and/or throat which may cause difficulty breathing or swallowing and wheezing occur rarely but may require treatment right away. Severe skin reactions have also been reported. Include on your medical history/personal profile all of the other medicines you are taking or plan to take while you are on VIOXX, even other medicines that you can get without a prescription. VIOXX has significant drug interactions with : - ACE inhibitors (medicines used for high blood pressure and heart failure). The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. - Serious kidney problems occur rarely, including acute kidney failure and worsening of chronic kidney failure. This medication may cause stomach upset, heartburn, headache, dizziness or drowsiness. If these symptoms persist or worsen, notify your doctor promptly. Inform your doctor promptly if you develop: persistent stomach pain, rapid heart rate. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. Include on your medical history/personal profile all of the other medicines you are taking or plan to take while you are on CELEBREX, even other medicines that you can get without a prescription. |